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Introduzzjoniu applikazzjonita CAS Nru.2378-95-2|N-[4-(methylamino)benzoyl]-L-glutamate tad-dietil
diethyl N-[4-(methylamino)benzoyl]-L-glutamate huwa prodrug li huwa metabolizzat għal (S)-diethyl 2-({4-aminobenzamido)pentanedioate, li jinibixxi l-enżima dihydrofolate reductase. Dan jipprevjeni s-sintesi ta 'tetrahydrofolate, kofattur essenzjali fis-sintesi ta' aċidi nuklejċi u aċidi amminiċi. Intwera li l-antibijotiku huwa attiv kontra batterji bħal Mycobacterium tuberculosis u Staphylococcus aureus, iżda mhux kontra ċelloli tal-mammiferi.
Sinonimi:
(S)-Dietil 2-(4-(methylamino)benzamido)pentanedjoate;
(2S)-2-[[4-(methylamino)benzoyl]amino]pentanedjoate tad-dietil;
Ester tad-dietil tal-aċidu N-(p-Methylaminobenzoyl)glutamiku;
diethyl N-(p-methylaminobenzoyl)-L-glutamate;
(S)-Dietil 2-(4-(methylamino)benzamido)pentanedjoate;
PN-Methylaminobenzoyl Aċidu Glutamiku Ester tad-Dietil;
dietil N-<4-(methylamino)benzoyl>AC1Q63IM;
N-[4-(metilamino)benzoil]-L-glutamat tad-dietil;
4-(methylamino)benzoyl-L-glutamate tad-dietil;
diethyl p-methylaminobenzoyl-L-glutamate;
N-(4-Methylaminobenzoyl)-L-Aċidu Glutamiku Ester tad-dietil;
N-(pN-methylaminobenzoyl)glutamat tad-dietil;
etil N-[p-(Methylamino)Benzoyl]-L-Glutamate;
dietil<4-(N-methylamino)benzoyl>-L-glutamat;
Speċifikazzjoni ta' CAS Nru.2378-95-2|N-[4-(methylamino)benzoyl]-L-glutamate tad-dietil
|
OĠĠETTI |
SPEĊIFIKAZZJONI |
|
CAS |
2378-95-2 |
|
MF |
C17H24N2O5 |
|
MW |
336.38 |
|
Punt tat-tidwib |
88-89 grad |
|
Densità |
1.165±0.06 g/cm3(Imbassar) |
|
Punt tat-togħlija |
518.3±50.0 grad (Imbassar) |
|
indiċi refrattiv |
1.536 |
|
Flash Point |
450.1ºC |
|
Ħażna |
Żomm f'post mudlam, Issiġillat f'xott, Temperatura tal-kamra |
Package u trasportta’ Introduzzjoni u applikazzjoni ta’CAS Nru.2378-95-2|N-[4-(methylamino)benzoyl]-L-glutamate tad-dietil
Pakkett:0.1g, 1g, 5g, 25g, 100g, 500g, 1kg
Trasport: bil-kurrier/ bl-ajru/ bil-baħar
Artikoli RelatatitaCAS Nru.2378-95-2|N-[4-(methylamino)benzoyl]-L-glutamate tad-dietil
[Sinteżi tad-dietil N-[p-(methylamino) benzoyl]-L-glutamate].
C Tian, SX Zhou, B Wang, XL Deng, Y Guo… - Beijing da xue xue …, 2008 - europepmc.org
… L-użu tad-dietil N-(p-aminobenzoyl)-L-glutamate (2) bħala materjal tal-bidu permezz ta’ proċess ta’ pot wieħed
tal-benżilazzjoni u tal-metilazzjoni, id-dietil N-[p-(methylamino)benzoyl ]-L-glutamate (3) huwa...
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